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HIV envelope: challenges and opportunities for development of entry inhibitors

The HIV envelope proteins glycoprotein 120 (gp120) and glycoprotein 41 (gp41) play crucial roles in HIV entry, therefore they are of extreme interest in the development of novel therapeutics. Studies using diverse methods, including structural biology and mutagenesis, have resulted in a detailed mod...

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Hlavní autor: Caffrey, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071980/
https://ncbi.nlm.nih.gov/pubmed/21377881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2011.02.001
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