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HIV envelope: challenges and opportunities for development of entry inhibitors

The HIV envelope proteins glycoprotein 120 (gp120) and glycoprotein 41 (gp41) play crucial roles in HIV entry, therefore they are of extreme interest in the development of novel therapeutics. Studies using diverse methods, including structural biology and mutagenesis, have resulted in a detailed mod...

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Autor principal: Caffrey, Michael
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071980/
https://ncbi.nlm.nih.gov/pubmed/21377881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2011.02.001
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