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Long Telomeres are Preferentially Extended During Recombination-Mediated Telomere Maintenance
Most human somatic cells do not express telomerase. Consequently, with each cell division their telomeres progressively shorten until replicative senescence is induced. Approximately 15% of human cancers maintain their telomeres using telomerase-independent, recombination-based mechanisms collective...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071861/ https://ncbi.nlm.nih.gov/pubmed/21441915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2034 |
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