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Long Telomeres are Preferentially Extended During Recombination-Mediated Telomere Maintenance

Most human somatic cells do not express telomerase. Consequently, with each cell division their telomeres progressively shorten until replicative senescence is induced. Approximately 15% of human cancers maintain their telomeres using telomerase-independent, recombination-based mechanisms collective...

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Hlavní autoři: Chang, Michael, Dittmar, John C., Rothstein, Rodney
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071861/
https://ncbi.nlm.nih.gov/pubmed/21441915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2034
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