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Choreography of Recombination Proteins during the DNA Damage Response
Genome integrity is frequently challenged by DNA lesions from both endogenous and exogenous sources. A single DNA double-strand break (DSB) is lethal if unrepaired and may lead to loss of heterozygosity, mutations, deletions, genomic rearrangements and chromosome loss if repaired improperly. Such ge...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729071/ https://ncbi.nlm.nih.gov/pubmed/19473884 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.04.007 |
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