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Choreography of Recombination Proteins during the DNA Damage Response

Genome integrity is frequently challenged by DNA lesions from both endogenous and exogenous sources. A single DNA double-strand break (DSB) is lethal if unrepaired and may lead to loss of heterozygosity, mutations, deletions, genomic rearrangements and chromosome loss if repaired improperly. Such ge...

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Dettagli Bibliografici
Autori principali: Lisby, Michael, Rothstein, Rodney
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729071/
https://ncbi.nlm.nih.gov/pubmed/19473884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.04.007
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