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The Slx5-Slx8 Complex Affects Sumoylation of DNA Repair Proteins and Negatively Regulates Recombination

Recombination is important for repairing DNA lesions, yet it can also lead to genomic rearrangements. This process must be regulated, and recently, sumoylation-mediated mechanisms were found to inhibit Rad51-dependent recombination. Here, we report that the absence of the Slx5-Slx8 complex, a newly...

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Detalhes bibliográficos
Main Authors: Burgess, Rebecca C., Rahman, Sadia, Lisby, Michael, Rothstein, Rodney, Zhao, Xiaolan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1952148/
https://ncbi.nlm.nih.gov/pubmed/17591698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00787-07
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