Dopaminergic Neuronal Loss, Reduced Neurite Complexity and Autophagic Abnormalities in Transgenic Mice Expressing G2019S Mutant LRRK2

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause late-onset, autosomal dominant familial Parkinson's disease (PD) and also contribute to idiopathic PD. LRRK2 mutations represent the most common cause of PD with clinical and neurochemical features that are largely indistinguishab...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ramonet, David, Daher, João Paulo L., Lin, Brian M., Stafa, Klodjan, Kim, Jaekwang, Banerjee, Rebecca, Westerlund, Marie, Pletnikova, Olga, Glauser, Liliane, Yang, Lichuan, Liu, Ying, Swing, Deborah A., Beal, M. Flint, Troncoso, Juan C., McCaffery, J. Michael, Jenkins, Nancy A., Copeland, Neal G., Galter, Dagmar, Thomas, Bobby, Lee, Michael K., Dawson, Ted M., Dawson, Valina L., Moore, Darren J.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2011
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071839/
https://ncbi.nlm.nih.gov/pubmed/21494637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018568
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