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Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria

Hepatocyte growth factor (HGF) is a potent antifibrotic protein that inhibits kidney fibrosis through several mechanisms. To study its role in podocyte homeostasis, injury, and repair in vivo, we generated conditional knockout mice in which the HGF receptor, c-met, was specifically deleted in podocy...

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Détails bibliographiques
Auteurs principaux: Dai, Chunsun, Saleem, Moin A., Holzman, Lawrence B., Mathieson, Peter, Liu, Youhua
Format: Artigo
Langue:Inglês
Publié: 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071594/
https://ncbi.nlm.nih.gov/pubmed/20375988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2010.40
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