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Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins

Clinical experience with adenovirus vectors has highlighted the need for improved delivery and targeting. Tumour-associated endothelium offers an additional mechanism for enhanced viral uptake into tumours which is accessible for systemic gene delivery. Building on expertise in using polymer ‘stealt...

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Main Authors: Bachtarzi, Houria, Stevenson, Mark, Šubr, Vladimir, Ulbrich, Karel, Seymour, Leonard W., Fisher, Kerry D.
格式: Artigo
語言:Inglês
出版: Elsevier Science Publishers 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071491/
https://ncbi.nlm.nih.gov/pubmed/20965218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.011
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