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Targeting adenovirus gene delivery to activated tumour-associated vasculature via endothelial selectins

Clinical experience with adenovirus vectors has highlighted the need for improved delivery and targeting. Tumour-associated endothelium offers an additional mechanism for enhanced viral uptake into tumours which is accessible for systemic gene delivery. Building on expertise in using polymer ‘stealt...

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Detalhes bibliográficos
Main Authors: Bachtarzi, Houria, Stevenson, Mark, Šubr, Vladimir, Ulbrich, Karel, Seymour, Leonard W., Fisher, Kerry D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science Publishers 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071491/
https://ncbi.nlm.nih.gov/pubmed/20965218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.011
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