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PAX7-FKHR TRANSCRIPTIONAL ACTIVITY IS ENHANCED BY TRANSCRIPTIONALLY REPRESSED MYOD
Alveolar rhabdomyosarcoma (ARMS) are characterized by the expression of chimeric transcription factors Pax3-FKHR and Pax7-FKHR, due to chromosomal translocations fusing PAX3 or PAX7 with the FKHR gene. Although ARMS exhibits a muscle lineage phenotype, the cells evade terminal differentiation despit...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071457/ https://ncbi.nlm.nih.gov/pubmed/21321994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23057 |
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