NEDD4 REGULATES PAX7 LEVELS PROMOTING ACTIVATION OF THE DIFFERENTIATION PROGRAM IN SKELETAL MUSCLE PRECURSORS

The transcription factor Pax7 regulates skeletal muscle stem cell (satellite cells) specification and maintenance through various mechanisms, including repressing the activity of the muscle regulatory factor MyoD. Hence, Pax7-to-MyoD protein ratios can determine maintenance of the committed-undiffer...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: Bustos, Francisco, de la Vega, Eduardo, Cabezas, Felipe, Thompson, James, Cornelison, DDW, Olwin, Bradley B., Yates, John R., Olguín, Hugo C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4579044/
https://ncbi.nlm.nih.gov/pubmed/26304770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2125
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