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A novel suicide substrate for DNA topoisomerases and site-specific recombinases.

DNA topoisomerases and DNA site-specific recombinases are biologically important enzymes involved in a diverse set of cellular processes. We show that replacement of a phosphodiester linkage by a 5'-bridging phosphorothioate linkage creates an efficient suicide substrate for calf thymus topoiso...

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Main Authors: Burgin, A B, Huizenga, B N, Nash, H A
Format: Artigo
Jezik:Inglês
Izdano: 1995
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC307138/
https://ncbi.nlm.nih.gov/pubmed/7659520
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