A novel suicide substrate for DNA topoisomerases and site-specific recombinases.
DNA topoisomerases and DNA site-specific recombinases are biologically important enzymes involved in a diverse set of cellular processes. We show that replacement of a phosphodiester linkage by a 5'-bridging phosphorothioate linkage creates an efficient suicide substrate for calf thymus topoisomeras...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1995
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307138/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7659520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.15.2973 |
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