Collagenolytic Activities of the Major Secreted Cathepsin L Peptidases Involved in the Virulence of the Helminth Pathogen, Fasciola hepatica

BACKGROUND: The temporal expression and secretion of distinct members of a family of virulence-associated cathepsin L cysteine peptidases (FhCL) correlates with the entry and migration of the helminth pathogen Fasciola hepatica in the host. Thus, infective larvae traversing the gut wall secrete cath...

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Detalhes bibliográficos
Main Authors: Robinson, Mark W., Corvo, Ileana, Jones, Peter M., George, Anthony M., Padula, Matthew P., To, Joyce, Cancela, Martin, Rinaldi, Gabriel, Tort, Jose F., Roche, Leda, Dalton, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071364/
https://ncbi.nlm.nih.gov/pubmed/21483711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001012
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