In vivo profiling of hypoxic gene expression in gliomas using the hypoxia marker EF5 and laser-capture microdissection

Hypoxia is a key determinant of tumor aggressiveness, yet little is known regarding hypoxic global gene regulation in vivo. We have employed the hypoxia marker EF5 coupled with laser capture microdissection to isolate RNA from viable hypoxic and normoxic regions of 9L experimental gliomas. Through m...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Marotta, Diane, Karar, Jayashree, Jenkins, W. Timothy, Kumanova, Monika, Jenkins, Kevin W., Tobias, John W., Baldwin, Donald, Hatzigeorgiou, Artemis, Alexiou, Panagiotis, Evans, Sydney M., Alarcon, Rodolfo, Maity, Amit, Koch, Cameron, Koumenis, Constantinos
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071295/
https://ncbi.nlm.nih.gov/pubmed/21266355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3061
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