Target sequence-specific inhibition of HIV-1 replication by ribozymes directed to tat RNA.
The structural motif formed between a hammerhead ribozyme and its substrate consists of three RNA double helices in which the sequence 5' to the XUY is termed helix I and the sequence 3' to the XUY helix III. Two hammerhead ribozymes targeted to the tat gene of HIV-1SF2 were designed to study target...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1995
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307129/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7544887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.15.2909 |
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