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Kinetic Isotope Effects of L-Dopa Decarboxylase

A mixed centroid path integral and free energy perturbation method (PI-FEP/UM) has been used to investigate the primary carbon and secondary hydrogen kinetic isotope effects (KIEs) in the amino acid decarboxylation of L-Dopa catalyzed by the enzyme L-Dopa decarboxylase (DDC) along with the correspon...

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Autors principals: Lin, Yen-lin, Gao, Jiali
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071286/
https://ncbi.nlm.nih.gov/pubmed/21366322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja108209w
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