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Internal Proton Transfer in the External Pyridoxal 5′-Phosphate Schiff Base in Dopa Decarboxylase
Combined quantum mechanical and molecular mechanical (QM/MM) simulations of dopa decarboxylase have been carried out to elucidate the factors that contribute to the tautomeric equilibrium of the intramolecular proton transfer in the external PLP–L-dopa Schiff base. The presence of a carboxylate anio...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827857/ https://ncbi.nlm.nih.gov/pubmed/19938875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901790e |
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