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Attenuating Smac Mimetic Compound 3-induced NF-κB Activation by Luteolin Leads to Synergistic Cytotoxicity in Cancer Cells
Smac mimetics are potential anticancer therapeutics selectively killing cancer cells through autocrine tumor necrosis factor (TNF)-mediated apoptosis pathway. Our recent study reveal that the Smac mimetic compound 3 (SMC3)-activated NF-κB protects cancer cells against apoptosis, thus blunting SMC3’s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071149/ https://ncbi.nlm.nih.gov/pubmed/19739098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22346 |
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