Alternative splicing and genomic structure of the AML1 gene involved in acute myeloid leukemia.

We previously isolated the AML1 gene, which is rearranged by the t(8;21) translocation in acute myeloid leukemia. The AML1 gene is highly homologous to the Drosophila segmentation gene runt and the mouse transcription factor PEBP2 alpha subunit gene. This region of homology, called the Runt domain,...

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Bibliographische Detailangaben
Hauptverfasser: Miyoshi, H, Ohira, M, Shimizu, K, Mitani, K, Hirai, H, Imai, T, Yokoyama, K, Soeda, E, Ohki, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307102/
https://ncbi.nlm.nih.gov/pubmed/7651838
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