The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity

Heterochromatin integrity is crucial for genome stability and regulation of gene expression, but the factors involved in mammalian heterochromatin biology are only incompletely understood. Here we identify the oncoprotein DEK, an abundant nuclear protein with a previously enigmatic in vivo function,...

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Autors principals: Kappes, Ferdinand, Waldmann, Tanja, Mathew, Veena, Yu, Jindan, Zhang, Ling, Khodadoust, Michael S., Chinnaiyan, Arul M., Luger, Karolin, Erhardt, Sylvia, Schneider, Robert, Markovitz, David M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2011
Matèries:
Research Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070930/
https://ncbi.nlm.nih.gov/pubmed/21460035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.2036411
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