Synthesis of oligodeoxyribonucleotide N3'-->P5' phosphoramidates.

An efficient synthesis of the novel nucleic acid analogs oligodeoxyribonucleotide N3'-->P5' phosphoramidates, where the 3'-oxygen is substituted by a 3'-nitrogen, is described. Synthesis of the title compounds was accomplished by the following synthetic steps. First, 5'-O-DMT base-protected-3'-amino...

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Publicat a:	Nucleic Acids Res
Autors principals:	Chen, J K, Schultz, R G, Lloyd, D H, Gryaznov, S M
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1995
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7651827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.14.2661
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