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Targeted Mutations in the Na,K-ATPase Alpha 2 Isoform Confer Ouabain Resistance and Result in Abnormal Behavior in Mice

Sodium and potassium-activated adenosine triphosphatases (Na,K-ATPase) are ubiquitous, participate in osmotic balance and membrane potential, and are composed of α, β, and γ subunits. The α subunit is required for the catalytic and transport properties of the enzyme and contains binding sites for ca...

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Autors principals: Schaefer, Tori L., Lingrel, Jerry B, Moseley, Amy E., Vorhees, Charles V., Williams, Michael T.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070835/
https://ncbi.nlm.nih.gov/pubmed/20936682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20870
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