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Optimized Allele-Specific Real-Time PCR Assays for the Detection of Common Mutations in KRAS and BRAF

Mutations in the oncogenes KRAS and BRAF have been identified as prognostic factors in patients with colorectal diseases and as predictors of negative outcome in epidermal growth factor receptor–targeted therapies. Therefore, accurate mutation detection in both genes, KRAS and BRAF, is of increasing...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lang, Alois H., Drexel, Heinz, Geller-Rhomberg, Simone, Stark, Nicole, Winder, Thomas, Geiger, Kathrin, Muendlein, Axel
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Investigative Pathology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070579/
https://ncbi.nlm.nih.gov/pubmed/21227391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.11.007
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