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Optimized Allele-Specific Real-Time PCR Assays for the Detection of Common Mutations in KRAS and BRAF
Mutations in the oncogenes KRAS and BRAF have been identified as prognostic factors in patients with colorectal diseases and as predictors of negative outcome in epidermal growth factor receptor–targeted therapies. Therefore, accurate mutation detection in both genes, KRAS and BRAF, is of increasing...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Investigative Pathology
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3070579/ https://ncbi.nlm.nih.gov/pubmed/21227391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.11.007 |
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