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Optimized Allele-Specific Real-Time PCR Assays for the Detection of Common Mutations in KRAS and BRAF

Mutations in the oncogenes KRAS and BRAF have been identified as prognostic factors in patients with colorectal diseases and as predictors of negative outcome in epidermal growth factor receptor–targeted therapies. Therefore, accurate mutation detection in both genes, KRAS and BRAF, is of increasing...

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Bibliografiska uppgifter
Huvudupphovsmän: Lang, Alois H., Drexel, Heinz, Geller-Rhomberg, Simone, Stark, Nicole, Winder, Thomas, Geiger, Kathrin, Muendlein, Axel
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070579/
https://ncbi.nlm.nih.gov/pubmed/21227391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2010.11.007
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