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Fibrinogen Deficiency Increases Liver Injury and Early Growth Response-1 (Egr-1) Expression in a Model of Chronic Xenobiotic-Induced Cholestasis

Chronic cholestatic liver injury induced by cholestasis in rodents is associated with hepatic fibrin deposition, and we found evidence of fibrin deposition in livers of patients with cholestasis. Key components of the fibrinolytic pathway modulate cholestatic liver injury by regulating activation of...

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מידע ביבליוגרפי
Main Authors: Luyendyk, James P., Kassel, Karen M., Allen, Katryn, Guo, Grace L., Li, Guodong, Cantor, Glenn H., Copple, Bryan L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Investigative Pathology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070556/
https://ncbi.nlm.nih.gov/pubmed/21356363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.11.064
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