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A Screenable in vivo Assay to Study Proteostasis Networks in Caenorhabditis elegans

In eukaryotic cells, the ubiquitin/proteasome system (UPS) is a key determinant of proteostasis as it regulates the turnover of damaged proteins. However, it is still unclear how the UPS integrates intrinsic and environmental challenges to promote organismal development and survival. Here, we set up...

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Detalhes bibliográficos
Main Authors: Segref, Alexandra, Torres, Serena, Hoppe, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070531/
https://ncbi.nlm.nih.gov/pubmed/21288877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.126797
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