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Environmental and Genetic Stressors and the Unfolded Protein Response in Exocrine Pancreatic Function – A Hypothesis

The exocrine pancreas has the greatest protein synthetic capacity of any mammalian organ and is challenged with the synthesis, processing and transporting a large load of digestive enzymes. Based on recent findings we present a hypothesis proposing that mutations in the digestive enzymes and environ...

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Detalhes bibliográficos
Main Authors: Pandol, Stephen J., Gorelick, Fred S., Lugea, Aurelia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070477/
https://ncbi.nlm.nih.gov/pubmed/21483727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2011.00008
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