Adaptive Unfolded Protein Response Attenuates Alcohol-induced Pancreatic Damage

BACKGROUND & AIMS: Endoplasmic reticulum (ER) stress responses (collectively known the unfolded protein response, UPR) have important roles in several human disorders, but their contribution to alcoholic pancreatitis is not known. We investigated the role of X box-binding protein 1 (XBP1), an UP...

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Bibliografiske detaljer
Main Authors: Lugea, Aurelia, Tischler, David, Nguyen, Janie, Gong, Jun, Gukovsky, Ilya, French, Samuel W., Gorelick, Fred S., Pandol, Stephen J.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057335/
https://ncbi.nlm.nih.gov/pubmed/21111739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.11.038
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