Adaptive Unfolded Protein Response Attenuates Alcohol-induced Pancreatic Damage

BACKGROUND & AIMS: Endoplasmic reticulum (ER) stress responses (collectively known the unfolded protein response, UPR) have important roles in several human disorders, but their contribution to alcoholic pancreatitis is not known. We investigated the role of X box-binding protein 1 (XBP1), an UP...

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Autores principales: Lugea, Aurelia, Tischler, David, Nguyen, Janie, Gong, Jun, Gukovsky, Ilya, French, Samuel W., Gorelick, Fred S., Pandol, Stephen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057335/
https://ncbi.nlm.nih.gov/pubmed/21111739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.11.038
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