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Ovarioleukodystrophy: report of a case with the c.338G>A (p.Arg113His) mutation on exon 3 and the c.896G>A (p.Arg299His) mutation on exon 7 of the EIF2B5 gene

The authors present a 28-year-old lady with progressive neurological deterioration beginning in childhood. She had clinical, radiological and genetic features of ovarioleukodystrophy. This is part of the spectrum of vanishing white matter disease and the first such case reported in the UK. The autho...

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Detalhes bibliográficos
Main Authors: Imam, Ibrahim, Brown, Jeremy, Lee, Philip, Thomas, P K, Manji, Hadi
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070385/
https://ncbi.nlm.nih.gov/pubmed/22699478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr.11.2010.3552
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