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Ovarioleukodystrophy: report of a case with the c.338G>A (p.Arg113His) mutation on exon 3 and the c.896G>A (p.Arg299His) mutation on exon 7 of the EIF2B5 gene

The authors present a 28-year-old lady with progressive neurological deterioration beginning in childhood. She had clinical, radiological and genetic features of ovarioleukodystrophy. This is part of the spectrum of vanishing white matter disease and the first such case reported in the UK. The autho...

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Bibliografske podrobnosti
Main Authors: Imam, Ibrahim, Brown, Jeremy, Lee, Philip, Thomas, P K, Manji, Hadi
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070385/
https://ncbi.nlm.nih.gov/pubmed/22699478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bcr.11.2010.3552
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