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New insights into p53 activation

The tumor suppressor p53 is a multifunctional, highly regulated, and promoter-specific transcriptional factor that is uniquely sensitive to DNA damage and cellular stress signaling. The mechanisms by which p53 directs a damaged cell down either a cell growth arrest or an apoptotic pathway remain poo...

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Detalhes bibliográficos
Main Authors: Brooks, Christopher L, Gu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070262/
https://ncbi.nlm.nih.gov/pubmed/20404858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.53
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