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DARPins: An Efficient Targeting Domain for Lentiviral Vectors

We have recently developed a retargeting system for lentiviral vectors (LVs) that relies on the pseudotyping of LVs with engineered measles virus (MV) glycoproteins (hemagglutinin (H) and fusion protein (F)). Specificity is provided through display of a single-chain antibody (scFv) as targeting doma...

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Detalhes bibliográficos
Main Authors: Münch, Robert C, Mühlebach, Michael D, Schaser, Thomas, Kneissl, Sabrina, Jost, Christian, Plückthun, Andreas, Cichutek, Klaus, Buchholz, Christian J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070099/
https://ncbi.nlm.nih.gov/pubmed/21224833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.298
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