Differential distribution of heparan sulfate glycoforms and elevated expression of heparan sulfate biosynthetic enzyme genes in the brain of mucopolysaccharidosis IIIB mice

The primary pathology in mucopolysaccharidosis (MPS) IIIB is lysosomal storage of heparan sulfate (HS) glycosaminoglycans, leading to complex neuropathology and dysfunction, for which the detailed mechanisms remain unclear. Using antibodies that recognize specific HS glycoforms, we demonstrate diffe...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: McCarty, Douglas M., DiRosario, Julianne, Gulaid, Kadra, Killedar, Smruti, Oosterhof, Arie, van Kuppevelt, Toin H., Martin, Paul T., Fu, Haiyan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer US 2011
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Original Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070083/
https://ncbi.nlm.nih.gov/pubmed/21225451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-010-9230-x
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