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Attenuation of the Lysosomal Death Pathway by Lysosomal Cholesterol Accumulation

In the past decade, lysosomal membrane permeabilization (LMP) has emerged as a significant component of cell death signaling. The mechanisms by which lysosomal stability is regulated are not yet fully understood, but changes in the lysosomal membrane lipid composition have been suggested to be invol...

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Autors principals: Appelqvist, Hanna, Nilsson, Cathrine, Garner, Brett, Brown, Andrew J., Kågedal, Katarina, Öllinger, Karin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069902/
https://ncbi.nlm.nih.gov/pubmed/21281795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.030
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