Attenuation of the Lysosomal Death Pathway by Lysosomal Cholesterol Accumulation

In the past decade, lysosomal membrane permeabilization (LMP) has emerged as a significant component of cell death signaling. The mechanisms by which lysosomal stability is regulated are not yet fully understood, but changes in the lysosomal membrane lipid composition have been suggested to be invol...

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Main Authors: Appelqvist, Hanna, Nilsson, Cathrine, Garner, Brett, Brown, Andrew J., Kågedal, Katarina, Öllinger, Karin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069902/
https://ncbi.nlm.nih.gov/pubmed/21281795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.030
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