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Mast Cells Are an Essential Component of Human Radiation Proctitis and Contribute to Experimental Colorectal Damage in Mice

Radiation proctitis is characterized by mucosal inflammation followed by adverse chronic tissue remodeling and is associated with substantial morbidity and mortality. Mast cell hyperplasia has been associated with diseases characterized by pathological tissue remodeling and fibrosis. Rectal tissue f...

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Main Authors: Blirando, Karl, Milliat, Fabien, Martelly, Isabelle, Sabourin, Jean-Christophe, Benderitter, Marc, François, Agnès
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069878/
https://ncbi.nlm.nih.gov/pubmed/21281796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.003
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