Essential Role of Plasminogen Activator Inhibitor Type-1 in Radiation Enteropathy

Intestinal radiation injury is a dose-limiting factor in radiation therapy for abdominal and pelvic cancers. Because transforming growth factor-β1 is a key mediator involved in radiation-induced damage, we hypothesized that its target gene, plasminogen activator inhibitor type 1 (PAI-1), is an essen...

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Autores principales: Milliat, Fabien, Sabourin, Jean-Christophe, Tarlet, Georges, Holler, Valerie, Deutsch, Eric, Buard, Valérie, Tamarat, Radia, Atfi, Azeddine, Benderitter, Marc, François, Agnès
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2008
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258261/
https://ncbi.nlm.nih.gov/pubmed/18276785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070930
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