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A conditional probability analysis of cystic fibrosis transmembrane conductance regulator gating indicates that ATP has multiple effects during the gating cycle

ATP-binding cassette (ABC) transporters bind and hydrolyze ATP. In the cystic fibrosis transmembrane conductance regulator Cl(−) channel, this interaction with ATP generates a gating cycle between a closed (C) and two open (O1 and O2) conformations. To understand better how ATP controls channel acti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hennager, Daniel J., Ikuma, Mutsuhiro, Hoshi, Toshinori, Welsh, Michael J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The National Academy of Sciences 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC30698/
https://ncbi.nlm.nih.gov/pubmed/11248123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051633298
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