Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression

Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia (AML). It is characterized by the t(15;17)(q22;q11.2) chromosomal translocation that creates the promyelocytic leukemia–retinoic acid receptor α (PML-RARA) fusion oncogene. Although this fusion oncogene is known to initiate AP...

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Detaylı Bibliyografya
Asıl Yazarlar: Wartman, Lukas D., Larson, David E., Xiang, Zhifu, Ding, Li, Chen, Ken, Lin, Ling, Cahan, Patrick, Klco, Jeffery M., Welch, John S., Li, Cheng, Payton, Jacqueline E., Uy, Geoffrey L., Varghese, Nobish, Ries, Rhonda E., Hoock, Mieke, Koboldt, Daniel C., McLellan, Michael D., Schmidt, Heather, Fulton, Robert S., Abbott, Rachel M., Cook, Lisa, McGrath, Sean D., Fan, Xian, Dukes, Adam F., Vickery, Tammi, Kalicki, Joelle, Lamprecht, Tamara L., Graubert, Timothy A., Tomasson, Michael H., Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2011
Konular:
Technical Advance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069786/
https://ncbi.nlm.nih.gov/pubmed/21436584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45284
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