An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice

Pilocytic astrocytoma (PA) is the most common type of primary brain tumor in children and the second most frequent cancer in childhood. Children with incompletely resected PA represent a clinically challenging patient cohort for whom conventional adjuvant therapies are only moderately effective. Thi...

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Bibliografski detalji
Glavni autori: Gronych, Jan, Korshunov, Andrey, Bageritz, Josephine, Milde, Till, Jugold, Manfred, Hambardzumyan, Dolores, Remke, Marc, Hartmann, Christian, Witt, Hendrik, Jones, David T.W., Witt, Olaf, Heiland, Sabine, Bendszus, Martin, Holland, Eric C., Pfister, Stefan, Lichter, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2011
Teme:
Brief Report
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069779/
https://ncbi.nlm.nih.gov/pubmed/21403401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44656
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