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Functional Roles of a C-terminal Signaling Complex of Ca(V)1 Channels and A-kinase Anchoring Protein 15 in Brain Neurons

Regulation of Ca(V)1.2 channels in cardiac myocytes by the β-adrenergic pathway requires a signaling complex in which the proteolytically processed distal C-terminal domain acts as an autoinhibitor of channel activity and mediates up-regulation by the β-adrenergic receptor and PKA bound to A-kinase...

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Bibliografiske detaljer
Main Authors: Marshall, Misty R., Clark, John Patrick, Westenbroek, Ruth, Yu, Frank H., Scheuer, Todd, Catterall, William A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069463/
https://ncbi.nlm.nih.gov/pubmed/21224388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175257
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