Loading...

Dopamine modulation of neuronal Na(+) channels requires binding of A kinase-anchoring protein 15and PKA by a modified leucine zipper motif

In hippocampal pyramidal cells, dopamine acts at D1 receptors to reduce peak Na(+) currents by activation of phosphorylation by PKA anchored via an A kinase-anchoring protein (AKAP15). However, the mechanism by which AKAP15 anchors PKA to neuronal Na(+) channels is not known. By using a strategy of...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Few, W. Preston, Scheuer, Todd, Catterall, William A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1829284/
https://ncbi.nlm.nih.gov/pubmed/17360357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611619104
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!