Direct Activation of Human Phospholipase C by Its Well Known Inhibitor U73122

Phospholipase C (PLC) enzymes are an important family of regulatory proteins involved in numerous cellular functions, primarily through hydrolysis of the polar head group from inositol-containing membrane phospholipids. U73122 (1-(6-((17β-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-...

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Detalhes bibliográficos
Main Authors: Klein, Ryan R., Bourdon, David M., Costales, Chester L., Wagner, Craig D., White, Wendy L., Williams, Jon D., Hicks, Stephanie N., Sondek, John, Thakker, Dhiren R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069444/
https://ncbi.nlm.nih.gov/pubmed/21266572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191783
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