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The Intrinsically Disordered Nuclear Localization Signal and Phosphorylation Segments Distinguish the Membrane Affinity of Two Cytidylyltransferase Isoforms

Membrane phosphatidylcholine homeostasis is maintained in part by a sensing device in the key regulatory enzyme, CTP:phosphocholine cytidylyltransferase (CCT). CCT responds to decreases in membrane phosphatidylcholine content by reversible membrane binding and activation. Two prominent isoforms, CCT...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Dennis, Melissa K., Taneva, Svetla G., Cornell, Rosemary B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069438/
https://ncbi.nlm.nih.gov/pubmed/21303909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201715
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