Quantitative Analysis of Tat Peptide Binding to Import Carriers Reveals Unconventional Nuclear Transport Properties

A detailed study of nuclear import mediated by the HIV-1 Tat peptide ((47)YGRKKRRQRRR(57), Tat(RRR)) is reported. Fluorescence-based measurements, calibration of protein concentrations, and binding assays are exploited to address the physicochemical mechanisms of Tat peptide recognition by the class...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cardarelli, Francesco, Serresi, Michela, Albanese, Alberto, Bizzarri, Ranieri, Beltram, Fabio
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2011
विषय:
Molecular Biophysics
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069432/
https://ncbi.nlm.nih.gov/pubmed/21321119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203083
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