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Quantitative Analysis of Tat Peptide Binding to Import Carriers Reveals Unconventional Nuclear Transport Properties
A detailed study of nuclear import mediated by the HIV-1 Tat peptide ((47)YGRKKRRQRRR(57), Tat(RRR)) is reported. Fluorescence-based measurements, calibration of protein concentrations, and binding assays are exploited to address the physicochemical mechanisms of Tat peptide recognition by the class...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3069432/ https://ncbi.nlm.nih.gov/pubmed/21321119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203083 |
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