Up-regulation and Sustained Activation of Stat1 Are Essential for Interferon-γ (IFN-γ)-induced Dual Oxidase 2 (Duox2) and Dual Oxidase A2 (DuoxA2) Expression in Human Pancreatic Cancer Cell Lines

Dual oxidase 2 is a member of the NADPH oxidase (Nox) gene family that plays a critical role in the biosynthesis of thyroid hormone as well as in the inflammatory response of the upper airway mucosa and in wound healing, presumably through its ability to generate reactive oxygen species, including H...

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Main Authors: Wu, Yongzhong, Antony, Smitha, Juhasz, Agnes, Lu, Jiamo, Ge, Yun, Jiang, Guojian, Roy, Krishnendu, Doroshow, James H.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
Bioenergetics
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069428/
https://ncbi.nlm.nih.gov/pubmed/21321110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191031
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